Lavori del 2023

Giannelli R, Canale P, Del Carratore R, Falleni A, Bernardeschi M, Forini F, Biagi E, Curzio O, Bongioanni P.

Ultrastructural and molecular investigation on peripheral leukocytes in Alzheimer’s Disease patients.

Int. J. Mol. Sci. 2023, 24,7909; https://doi.org/10.3390/ijms24097909


Lazzeri G, Biagioni F, Ferrucci M, Puglisi-Allegra S, Lenzi P, Busceti CL,

Giannessi F, Fornai F.

The Relevance of Autophagy within Inner Ear in Baseline

Conditions and Tinnitus-Related Syndromes. Int J Mol Sci. 2023 Nov

23;24(23):16664. doi: 10.3390/ijms242316664. PMID: 38068993; PMCID: PMC10706730.


Lenzi P, Busceti CL, Lazzeri G, Ferese R, Biagioni F, Salvetti A, Pompili E,

De Franchis V, Puglisi-Allegra S, Frati A, Ferrucci M, Fornai F.

Autophagy Activation Associates with Suppression of Prion Protein and Improved

Mitochondrial Status in Glioblastoma Cells.

Cells. 2023 Jan 4;12(2):221. doi:

10.3390/cells12020221. PMID: 36672156; PMCID: PMC9857229.


Pepe G, Capocci L, Marracino F, Realini N, Lenzi P, Martinello K, Bovier TF,

Bichell TJ, Scarselli P, Di Cicco C, Bowman AB, Digilio FA, Fucile S, Fornai F,

Armirotti A, Parlato R, Di Pardo A, Maglione V.

Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's disease.

Mol Ther. 2023 Jan 4;31(1):282-299. doi: 10.1016/j.ymthe.2022.09.004.

Epub 2022 Sep 16. PMID: 36116006; PMCID: PMC9840122.


Pepe G, Lenzi P, Capocci L, Marracino F, Pizzati L, Scarselli P, Di Pardo A,

Fornai F, Maglione V.

Treatment with the Glycosphingolipid Modulator THI Rescues Myelin Integrity in the Striatum of R6/2 HD Mice.

Int J Mol Sci. 2023 Mar 22;24(6):5956. doi: 10.3390/ijms24065956. PMID: 36983032; PMCID: PMC10053002.